QScores-Archiver is a system for archiving quality scores from next generation sequencing data in FASTQ format using lossy transformations, lossless transformations, and compression. The software is available at the following link. See the accompanying README.html for more information.

The method represented by the QScores-Archiver software is described here:

R. Wan, V. N. Anh, and K. Asai. Transformations for the Compression of FASTQ Quality Scores of Next Generation Sequencing Data. Bioinformatics, 28(5):623-635, 2012 [Publisher]

This page was previously (but no longer) linked from my previous lab's web page (http://www.cb.k.u-tokyo.ac.jp/asailab/members/rwan) at the University of Tokyo (where all of this work was done).

Software page